Present Academic Position：

Professor in Musculoskeletal Oncology Division, Department of Orthopedic Surgery,

Faculty of Medicine, Chiang Mai University, Thailand.

Director of Musculoskeletal Science and Translational Research Center

Director of Center of Multidisciplinary Technology for Advance Medicine (CMUTEAM)

 

Education and Training:

2000 Degree of Doctor of Medicine (Second Class Honors).

2006 Certificate of Proficiency in Orthopedic Surgery, Thai Orthopedic Association, Medical Council, Thailand

2008 Visiting fellowship of Muskuloskeletal Oncology Surgery, Munster University Hospital, Munster, Germany.

2010 Philosophy of Doctor in “Apply Biological Science Program” at Chulabhorn Graduated Institute, Bangkok, Thailand.

2011 Clinical fellowship of Musculoskeletal Oncology and Lower Limb Reconstruction, University of British Columbia, Canada

 

Selected grants (After 2015)

2016-2018 Serine-theonine kinase receptor-associated protein (STRAP) for the progression of osteosarcoma Thailand Research Fund              

2016-2019 Identification of classifying factors of osteosarcoma for group-specifictreatments NSTDA, Thailand

2016-2017 ilver cluster research level, Chiang Mai University

2017-2019 Gold cluster research level, Chiang Mai University

2019-2022 Mycophenolate mofetil (MMF) as a repurposed drug for the treatment of osteosarcoma, NSTDA

2019-2022 Research center of excellence for Musculoskeletal Science and Translational Research, Chiang Mai University

2021-2023 Rare pediatric cancer group of Genomic Thailand

Selected publications (After 2021)

 1.    Mass Spectrometric-Based Proteomics for Biomarker Discovery in Osteosarcoma: Current Status and Future Direction.

Sirikaew N, Pruksakorn D, Chaiyawat P, Chutipongtanate S.

Int J Mol Sci. 2022 Aug 28;23(17):9741.

 2.    Descriptive epidemiology of soft tissue sarcomas and gastrointestinal stromal tumors in Thailand.

Klangjorhor J, Pongnikorn D, Sittiju P, Phanphaisarn A, Chaiyawat P, Teeyakasem P, Kongdang P, Moonmuang S, Waisri N, Daoprasert K, Wisanuyotin T, Santong C, Sitthikong S, Tuntarattanapong P, Prechawittayakul P, Pruksakorn D.

Sci Rep. 2022 Jul 27;12(1)

 3.    Clinical Implication of Circulating Tumor Cells Expressing Epithelial Mesenchymal Transition (EMT) and Cancer Stem Cell (CSC) Markers and Their Perspective in HCC: A Systematic Review.

Orrapin S, Udomruk S, Lapisatepun W, Moonmuang S, Phanphaisarn A, Phinyo P, Pruksakorn D, Chaiyawat P.

Cancers (Basel). 2022 Jul 11;14(14):3373.

 4.    Osteosarcoma-Specific Genes as a Diagnostic Tool and Clinical Predictor of Tumor Progression.

Sittiju P, Chaiyawat P, Pruksakorn D, Klangjorhor J, Wongrin W, Phinyo P, Kamolphiwong R, Phanphaisarn A, Teeyakasem P, Kongtawelert P, Pothacharoen P.

Biology (Basel). 2022 May 1;11(5):698.

 5.    Extracellular Vesicle-Mediated IL-1 Signaling in Response to Doxorubicin Activates PD-L1 Expression in Osteosarcoma Models.

Yati S, Silathapanasakul A, Thakaeng C, Chanasakulniyom M, Songtawee N, Porntadavity S, Pothacharoen P, Pruksakorn D, Kongtawelert P, Yenchitsomanus PT, Chanmee T.

Cells. 2022 Mar 18;11(6):1042.

 6.    Analysis of study designs and primary outcome measures in clinical trials of investigational suture materials.

Dukaew N, Sakuludomkan W, Na Takuathung M, Pruksakorn D, Punyodom W, Koonrungsesomboon N.

Expert Rev Med Devices. 2022 Mar;19(3):247-258.

 7.    Preclinical experimental models for assessing laxative activities of substances/products under investigation: a scoping review of the literature.

Kongdang P, Pruksakorn D, Koonrungsesomboon N.

Am J Transl Res. 2022 Feb 15;14(2):698-717.

 8.    Development of Clinical Prediction Rules for One-Year Postoperative Functional Outcome in Patients with Intertrochanteric Fractures: The Intertrochanteric Fracture Ambulatory Prediction (IT-AP) Tool.

Adulkasem N, Phinyo P, Khorana J, Pruksakorn D, Apivatthakakul T.Int J Environ Res Public Health. 2021 Dec 24;19(1):177.

 9.    An analysis of the incidence and survival rates of bone sarcoma patients in thailand: reports from population-based cancer registries 2001-2015.

Klangjorhor J, Pongnikorn D, Phanphaisarn A, Chaiyawat P, Teeyakasem P, Suksakit P, Pasena A, Udomruk S, Orrapin S, Pornwattanavate S, Waisri N, Daoprasert K, Wisanuyotin T, Santong C, Sangrajrang S, Sitthikong S, Tuntarattanapong P, Prechawittayakul P, Pruksakorn D.

Cancer Epidemiol. 2022 Feb;76:102056.

 10. TP53 mutational hot spots for Li-Fraumeni syndrome in Asian populations.

Lo Piccolo L, Jantrapirom S, Moonmuang S, Teeyakasem P,  Pasena A, Suksakit P, Charoenkwan P,Pruksakorn D, Koonrungsesomboon N.

Trop Med Int Health. 2021 Sep 3.

 11. Relationship Between O-GlcNAcase Expression and Prognosis of Patients With Osteosarcoma.

Sombutthaweesri T, Wu S, Chamusri N, Settakorn J,Pruksakorn D, Chaiyawat P, Sastraruji T, Krisanaprakornkit S, Supanchart C.

Appl Immunohistochem Mol Morphol. 2021 Aug 31.

 12. Size distribution of cell-free DNA in oncology.

Udomruk S, Orrapin S,Pruksakorn D, Chaiyawat P.

Crit Rev Oncol Hematol. 2021 Aug 28;166:

 13. Circulating Long Non-Coding RNAs as Novel Potential Biomarkers for Osteogenic Sarcoma.

Moonmuang S, Chaiyawat P, Jantrapirom S,Pruksakorn D, Lo Piccolo L. Cancers (Basel). 2021 Aug 21;13(16):4214.

 14. Biochemistry of Amaranthus polyphenols and their potential benefits on gut ecosystem: A comprehensive review of the literature.

Kongdang P, Dukaew N,Pruksakorn D, Koonrungsesomboon N. J Ethnopharmacol. 2021 Aug 20;281:114547.

 15. Mycophenolic acid and cancer risk in solid organ transplant recipients: Systematic review and meta-analysis.

Hirunsatitpron P, Hanprasertpong N, Noppakun K,Pruksakorn D, Teekachunhatean S, Koonrungsesomboon N.

Br J Clin Pharmacol. 2021 Jul 8.

 16. Prognostic Factors of 1-Year Postoperative Functional Outcomes of Older Patients with Intertrochanteric Fractures in Thailand: A Retrospective Cohort Study.

Adulkasem N, Phinyo P, Khorana J,Pruksakorn D, Apivatthakakul T.

Int J Environ Res Public Health. 2021 Jun 27;18(13):6896.

 17. Synthesis of propargylamine mycophenolate analogues and their selective cytotoxic activity towards neuroblastoma SH-SY5Y cell line.

Silalai P, Pruksakorn D, Chairoungdua A, Suksen K, Saeeng R. Bioorg

Med Chem Lett. 2021 Aug 1;45:128135.

 18. IMPDH2 and HPRT expression and a prognostic significance in preoperative and postoperative patients with osteosarcoma.

Chaiyawat P, Phanphaisarn A, Sirikaew N, Klangjorhor J, Thepbundit V, Teeyakasem P, Phinyo P,Pruksakorn D, Settakorn J.

Sci Rep. 2021 May 25;11(1):10887.

 19. Long noncoding RNA-dependent methylation of nonhistone proteins.

Jantrapirom S, Koonrungsesomboon N, Yoshida H, M Candeias M,Pruksakorn D, Lo Piccolo L.

Wiley Interdiscip Rev RNA. 2021 Apr 29:e1661